Resection Plus Post-operative Adjuvant Transcatheter Arterial Chemoembolization (TACE) Compared with Resection Alone for Hepatocellular Carcinoma: A Systematic Review and Meta-analysis
| Autor: | Michael Vinchill Chan, Ya Ruth Huo, Christine Chan |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Carcinoma Hepatocellular medicine.medical_treatment Subgroup analysis Gastroenterology Disease-Free Survival 030218 nuclear medicine & medical imaging law.invention Lesion 03 medical and health sciences 0302 clinical medicine Randomized controlled trial law Internal medicine Humans Medicine Radiology Nuclear Medicine and imaging Postoperative Period Chemoembolization Therapeutic Transcatheter arterial chemoembolization Postoperative Care business.industry Liver Neoplasms medicine.disease Treatment Outcome medicine.anatomical_structure Liver Meta-analysis Hepatocellular carcinoma medicine.symptom Cardiology and Cardiovascular Medicine business Adjuvant Artery |
| Zdroj: | CardioVascular and Interventional Radiology. 43:572-586 |
| ISSN: | 1432-086X 0174-1551 |
| DOI: | 10.1007/s00270-019-02392-6 |
| Popis: | Multiple studies have demonstrated adjuvant transcatheter arterial chemoembolization (aTACE) after resection improved outcomes compared to resection alone for patients with hepatocellular carcinoma (HCC). Unlike pre-operative TACE which targets a lesion, aTACE is administered in the proximal hepatic artery to destroy cancer cells within the remaining liver. This systematic review and meta-analysis aims to quantify this survival and disease-free survival (DFS) benefit. A search of five databases was performed from inception to 20 August 2019. A total of 26 studies (six randomized controlled trials) involving 7817 patients were included. Patients treated with resection plus aTACE had significantly better 1-year survival (OR, 2.53 [95% CI, 1.70–3.76, p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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