Severity of morphological lesion complexity affects fractional flow reserve in intermediate coronary stenosis

Autor: Akiyoshi Kurita, Soichiro Kumagai, Kazuyuki Maeda, Hirohiko Ando, Tetsuya Amano, Katsuhisa Waseda, Akihiro Suzuki, Shinichiro Sakurai, Masahiko Gosho, Hiroaki Takashima
Rok vydání: 2015
Předmět:
Zdroj: Journal of Cardiology. 66(3):239-245
ISSN: 0914-5087
DOI: 10.1016/j.jjcc.2014.11.004
Popis: BackgroundAlthough functional ischemia identification is important when determining revascularization, angiographic assessment alone is challenging in intermediate coronary stenosis. Previous studies have reported that lesion-specific characteristics affected the fractional flow reserve (FFR). However, the relationship between morphological lesion complexity and FFR has not yet been fully evaluated. This study aimed to evaluate the impact of morphological lesion complexity on FFR in intermediate coronary stenosis.MethodsA total of 109 consecutive patients with 136 intermediate coronary stenoses (visually estimated diameter stenosis: 40–70%) were assessed via quantitative coronary angiography, lesion-specific characteristics, and FFR. Indexed lesions were assessed according to 6 morphological lesion characteristics: eccentricity, bend, irregularity, calcification, bifurcation, and diffuse. The lesions were then classified into 3 groups according to the morphological severity count represented by the number of present characteristics (mild-complex: 0–1, moderate-complex: 2–3, and severe-complex: 4–6), and their functional severities were evaluated. Lesions with an FFR
Databáze: OpenAIRE