Hyperglycemia associated with seizure control in status epilepticus
| Autor: | Kittisak Sawanyawisuth, Somsak Tiamkao, Parinya Noppaklao, Piyawan Chiewthanakul |
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| Rok vydání: | 2015 |
| Předmět: |
Adult
Blood Glucose Male Pediatrics medicine.medical_specialty Status epilepticus Behavioral Neuroscience Epilepsy Status Epilepticus Recurrence Seizures medicine Seizure control Humans In patient Aged Retrospective Studies business.industry Mortality rate Middle Aged medicine.disease Thailand Neurology Anesthesia Hyperglycemia Logistic analysis Etiology Female Neurology (clinical) medicine.symptom business Low serum albumin |
| Zdroj: | Epilepsybehavior : EB. 49 |
| ISSN: | 1525-5069 |
| Popis: | Background Status epilepticus (SE) is a serious neurological condition and has a high mortality rate. Factors associated with seizure control measures in nonneurointensive care units (non-NICU) are limited. Methods Adult patients diagnosed with SE at Khon Kaen hospital, Thailand from October 1st, 2010 to September 30th, 2012 were enrolled. Patients were categorized as having controlled seizures and having uncontrolled seizures. Controlled seizures were defined as seizures that were aborted without any recurrence, while uncontrolled seizures were defined as unstoppable or recurrent seizures. Clinical factors were analyzed to find factors associated with uncontrolled SE. Results During the study period, there were 211 patients diagnosed with SE. Of those, 57 patients (27.01%) were in the group with controlled SE. Plasma glucose and serum albumin were two significant factors with adjusted ORs (95% CI) of 1.008 (1.001, 1.027) and 0.166 (0.059, 0.466) that differentiated patients with controlled seizures from patients with uncontrolled seizures. Central nervous system infections and cardiac arrests were also completely associated with the uncontrolled SE in the multivariate logistic analysis. Conclusions In the etiology of SE, high plasma glucose and low serum albumin levels were associated with uncontrolled seizures in patients with SE in the non-NICU setting. This article is part of a Special Issue entitled “Status Epilepticus”. |
| Databáze: | OpenAIRE |
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