Dichromacy: Color Vision Impairment and Consanguinity in Heterogenous Population of Pakistan
| Autor: | M. Aslamkhan, Mian Sahib Zar, Asif Hanif, Abdul Rehman Haris, Muhammad Shoaib Akhtar |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
Population Ethnic group Consanguinity Microbiology Population density Protanopia Epidemiology Ethnicity Medicine Pakistan Dichromacy education education.field_of_study business.industry Incidence (epidemiology) Deuteranopia Heterogenous Population medicine.disease QR1-502 Punjab Population study business Chiniot Demography |
| Zdroj: | The International Journal of Frontier Sciences, Vol 3, Iss 1 (2019) |
| ISSN: | 2618-0367 2618-0359 |
| DOI: | 10.37978/tijfs.v3i1.47 |
| Popis: | Background and Objectives: Dichromacy, an X-linked recessive disorder is identified worldwide, more in males than females. In European Caucasians, its incidence is 8% in males and 0.5% in females. In India, it is 8.73% in males and 1.69% in females, and in Iran, it is 8.18% in males and 0.43% in females. Population based epidemiological data about dichromacy in different ethnic groups in Pakistan is not available. The aim of this study was to find out the population prevalence of inherited red-green dichromacy in a heterogenous population of the district of Chiniot, Punjab, Pakistan, and to determine the impact of consanguinity and ethnicity. Methods: In this cross-sectional study, boys and girls of the higher secondary schools were examined in the three tehsils of district Chiniot. Pseudoisochromatic Ishihara Test has been employed for detection of dichromacy in the study population. The sample size was calculated statistically as 260, which was expanded to 705 and divided by population density of the three tehsils. Results: Screening of 359 males and 346 females revealed 19 (5.29%) dichromat males and only 2 (0.58%) females. The study population belonged to 23 castes / isonym groups. The consanguinity found in the district of Chiniot is 84.82% and in the dichromat families, it is 85.71%, of which 52.37% are first cousin. Interpretation & Conclusion: The study has shown that the incidence of dichromacy could be reduced through genetic counseling |
| Databáze: | OpenAIRE |
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