The complete genome sequence and molecular analysis of human hepatitis E virus genotype IV identified from a Korean patient
| Autor: | Seong Gyu Hwang, Jong-Hyun Kim, Haesun Yun, Sook Kyoung Kang, Sang Jong Park, Jeong Sim Kim, Jin Seon Kim, Sook Hyang Jeong, Youngmee Jee, Hyeok Jin Lee |
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| Rok vydání: | 2010 |
| Předmět: |
Genotype
viruses Molecular Sequence Data Genome Viral Biology medicine.disease_cause Genome Virus Hepatitis E virus Virology medicine Animals Humans Phylogeny Hepatitis Genetics Korea Base Sequence Nucleic acid sequence virus diseases Sequence Analysis DNA General Medicine Middle Aged medicine.disease Hepatitis E biology.organism_classification digestive system diseases Caliciviridae Female |
| Zdroj: | Archives of Virology. 155:1003-1008 |
| ISSN: | 1432-8798 0304-8608 |
| DOI: | 10.1007/s00705-010-0661-9 |
| Popis: | Hepatitis E virus (HEV) was originally identified as the etiological agent of non-HAV enterically transmitted hepatitis. One HEV strain (FJ763142) was identified from an acute viral hepatitis E patient with IgM anti-HEV in Korea. The complete genome sequence consisted of 7,238 nucleotides (nt) plus a 22-nt poly(A) tail. The strain belongs to genotype IV, with 91% homology compared with AB197674, which was found in a Japanese patient who had traveled to China. This finding suggests that HEV genotype IV already circulates in Korea, and this HEV might be the first example of an indigenous strain. |
| Databáze: | OpenAIRE |
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