Perinatal arterial ischemic stroke related to carotid artery occlusion
Autor: | Stéphane Chabrier, Frédéric Villega, Stephanie Garcia-Tarodo, Joel Victor Fluss, Sébastien Lebon, Béatrice Husson, Solene Ferey, Manoelle Kossorotoff, Vincent Muehlethaler, Michèle Granier |
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Rok vydání: | 2016 |
Předmět: |
Male
medicine.medical_specialty Placenta/pathology Magnetic resonance angiography Brain ischemia 03 medical and health sciences Intellectual Disability/etiology Stroke/diagnostic imaging/etiology 0302 clinical medicine Cerebral Palsy/etiology Pregnancy Risk Factors 030225 pediatrics Internal medicine medicine Humans cardiovascular diseases Thrombus Carotid Arteries/diagnostic imaging Stroke Arterial Occlusive Diseases/complications/diagnostic imaging Carotid Artery Diseases/complications/diagnostic imaging ddc:618 medicine.diagnostic_test business.industry Infant Newborn General Medicine Brain/diagnostic imaging medicine.disease Brain Ischemia/diagnostic imaging/etiology Cerebral Angiography Epilepsies Partial/etiology Developmental Disabilities/etiology Carotid artery occlusion Pediatrics Perinatology and Child Health Arterial Occlusive Diseases Etiology Cardiology Female Neurology (clinical) business Magnetic Resonance Angiography 030217 neurology & neurosurgery Cerebral angiography |
Zdroj: | European Journal of Paediatric Neurology, Vol. 20, No 4 (2016) pp. 639-48 |
ISSN: | 1090-3798 |
Popis: | Background The aetiology of perinatal arterial ischemic stroke remains speculative. It is however widely accepted that the aetiology is multifactorial, involving various maternal, placental, foetal and neonatal risk factors. A resulting thromboembolic process is hypothesized and the placenta identified as the most plausible source. An arteriopathy, as observed in a significant proportion of childhood ischemic stroke, is thought to be rare. Methods We report here five cases of perinatal stroke that differ from the vast majority by documented carotid occlusion, and add eleven other similar cases from the literature. Results In the majority, an intraluminal thrombus of placental origin is the most probable hypothesis, while in the remaining ones, one can reasonably presume a direct vessel wall injury related to a traumatic delivery, yet generally unproven by imaging. Conclusion We hypothesize that most of these cases share similar pathophysiology with the more common perinatal arterial ischemic stroke but differ by a persistent identified thrombus in the carotid artery at the time of first imaging, leading to a more severe and extended ischemic damage responsible for an adverse neurological outcome. |
Databáze: | OpenAIRE |
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