Transcatheter aortic valve replacement (TAVR): expanding indications to low-risk patients
| Autor: | Pablo Avanzas, Christian Dam, Hector Cubero-Gallego, Juan Meca |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Percutaneous Transcatheter aortic Review Article on Structural Heart Disease: The Revolution business.industry medicine.medical_treatment General Medicine 030204 cardiovascular system & hematology medicine.disease Lower risk law.invention Surgery 03 medical and health sciences Stenosis 0302 clinical medicine Randomized controlled trial Aortic valve replacement Valve replacement law Medicine In patient 030212 general & internal medicine business |
| Zdroj: | Ann Transl Med WOS:000561888400021 RUO. Repositorio Institucional de la Universidad de Oviedo instname |
| ISSN: | 2305-5847 2305-5839 |
| DOI: | 10.21037/atm.2020.03.155 |
| Popis: | Aortic stenosis (AS) is the most common cardiac valve disease in developed countries. Transcatheter aortic valve replacement (TAVR) for the treatment of severe symptomatic AS is an accepted therapy option for elderly patients with symptomatic severe AS. Nowadays, TAVR has revolutionized the treatment of AS with an exponential growth worldwide. Both the development of new generation valves and the experience of the operating teams have contributed significantly to decrease the complications rate after TAVR. Several randomized trials have reported similar short- and mid-term results, and even better than surgical aortic valve replacement (SAVR) in patients with high- or intermediate-risk. In addition, two comparison trials in low-risk patients have reported promising results. Therefore, in the future TAVR indications will expand, treating younger and younger patients, with less comorbidities and lower risk. However, the long-term durability of percutaneous prostheses is a matter of debate. The aim of this manuscript is to review available data that support to treat AS in low-risk patients and provide our perspective on the topic. |
| Databáze: | OpenAIRE |
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