Ten Year Clinical Experience with the CarboMedics Heart Valve Implants
| Autor: | Tomio Abe, Junichi Sakata, Masaru Tsukamoto, Kenji Kuwaki, Kanshi Komatsu |
|---|---|
| Rok vydání: | 2002 |
| Předmět: |
Adult
Male Aortic valve medicine.medical_specialty medicine.medical_treatment Heart Valve Diseases Biomedical Engineering Medicine (miscellaneous) Bioengineering Prosthesis Biomaterials Postoperative Complications Internal medicine Mitral valve medicine Humans Endocarditis Heart valve Survival rate Proportional Hazards Models business.industry Incidence (epidemiology) General Medicine Middle Aged medicine.disease Surgery Survival Rate Logistic Models Treatment Outcome medicine.anatomical_structure Embolism Heart Valve Prosthesis Cardiology Female business Follow-Up Studies |
| Zdroj: | Artificial Organs. 26:695-702 |
| ISSN: | 1525-1594 0160-564X |
| DOI: | 10.1046/j.1525-1594.2002.06964.x |
| Popis: | We reviewed the histories of 144 patients who underwent heart valve replacement with the CarboMedics prosthesis from 1990 to 2000. There were 74 males and 70 females, with a mean age of 52 years, including 69 aortic valve replacements, 48 mitral valve replacements, and 27 double (aortic and mitral) valve replacements. The mean duration of follow-up was 6.5 years. Early mortality was 7.6% (11 patients). Late deaths occurred in 14 patients, including cardiac-related late deaths in 9 and valve-related deaths in 3. The survival rate including early deaths was 84.7 +/- 3.2% at 5 years and 78 +/- 4.1% at 10 years. Preoperative New York Heart Association Class IV (p = 0.0001) was found to be a significant predictor of cardiac-related late death. Freedom rate from complications at 10 years were embolism 84.7 +/- 4.2% (linearized rate 1.8% per patient year), valve thrombosis 92.7 +/- 2.7% (linearized rate 0.8% per patient year), bleeding 95.6 +/- 2.6% (linearized rate 0.4% per patient year), reoperation 85.9 +/- 4% (linearized rate 1.5% per patient year), valve endocarditis 98.7 +/- 1.3% (linearized rate 0.1% per patient year), and nonstructural dysfunction 90 +/- 3.5% (linearized rate 1% per patient year). There was no structural deterioration. The early and long-term results with the CarboMedics heart valve implantation were acceptable, but valve thrombosis remains a concern in the present study. Further investigation for optimal anticoagulation therapy is necessary to reduce the incidence of valve thrombosis as well as embolic and bleeding complications. |
| Databáze: | OpenAIRE |
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