Physical activity in pregnancy prevents gestational diabetes: A meta-analysis
| Autor: | Aisha M. Mohamed, Suhail A.R. Doi, Luis Furuya-Kanamori, Egon Toft, Lukman Thalib, Omran A.H. Musa, Justin Clark |
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| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Adult
medicine.medical_specialty Adolescent Endocrinology Diabetes and Metabolism Pregnancy risk MEDLINE 030209 endocrinology & metabolism Overweight Gestational diabetes mellitus law.invention 03 medical and health sciences Young Adult 0302 clinical medicine Endocrinology Randomized controlled trial law Pregnancy Internal Medicine Medicine Humans 030212 general & internal medicine Obesity Exercise business.industry Obstetrics General Medicine Middle Aged medicine.disease Gestational diabetes Diabetes Gestational Meta-analysis Number needed to treat Gestation Female medicine.symptom business |
| Popis: | Aims The effectiveness of physical activity (PA) programs for prevention of gestational diabetes (GDM) lacks conclusive evidence. The aim of this study was to generate clear evidence regarding the effectiveness of physical activity programs in GDM prevention to guide clinical practice. Methods PubMed/Medline, ISI Web of Science, Scopus, and EMBASE were searched to identify the randomized trials (RCTs) published until June 2019. Randomised controlled trials enrolling women at high risk before the 20th week of gestation comparing the effect of PA interventions with usual care for prevention of GDM were retrieved. Data obtained were synthesised using a bias-adjusted model of meta-analysis. Results A total of 1467 adult women in 11 eligible trials were included. The risk of GDM was significantly lower with PA, but only when it was delivered in the healthcare facility (RR 0.53; 95% CI 0.38–0.74). The number needed to treat with PA in pregnancy (compared to usual care) to prevent one GDM event was 18 (95% CI 14 – 29). The overall effect of PA interventions regardless of location of the intervention was RR 0.69 (95% CI 0.51 – 0.94). Conclusions This study provides evidence that in-facility physical activity programs started before the 20th week of gestation can significantly decrease the incidence of GDM among women at high risk. |
| Databáze: | OpenAIRE |
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