Comparing hemodynamic and glycemic response to local anesthesia with epinephrine and without epinephrine in patients undergoing tooth extractions
| Autor: | Sameer Kaura, Rashi Bahl, Sumit Bansal, Paramjot Kaur |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Epinephrine
tooth extractions medicine.drug_class Diastole Hemodynamics 030204 cardiovascular system & hematology 03 medical and health sciences 0302 clinical medicine lignocaine HCl Medicine Local anesthesia Glycemic type II diabetes normotensive business.industry Local anesthetic 030206 dentistry Blood pressure Hemostasis Anesthesia Original Article Surgery Oral Surgery local anesthesia business medicine.drug |
| Zdroj: | National Journal of Maxillofacial Surgery |
| ISSN: | 0975-5950 |
| DOI: | 10.4103/0975-5950.201370 |
| Popis: | Introduction: Lignocaine with epinephrine as local anesthetic (LA) provides hemostasis and decreases the risk of systemic toxicity. The purpose of the present study was to investigate and compare the response of lignocaine with and without epinephrine to evaluate hemodynamic and metabolic response in normotensive and type II controlled diabetic patients. Material and Methods: A total of 50 patients (25 healthy and 25 controlled type II diabetics) undergoing multiple tooth extractions (age group of 20–80 years) were included in this prospective, randomised, clinical study. On their first visit, the patients were given 2% lignocaine HCl with 1:200,000 epinephrine, and 2% lignocaine HCl was given on the second visit, to carry out tooth extractions. Blood pressure (BP), pulse rate, oxygen saturation, and blood glucose estimations were done at definite intervals (before, immediately after, and 20 min after the administration of LA) on both the visits. Results: The increase in blood glucose concentration following the administration of 2% lignocaine HCl with 1:200,000 epinephrine was statistically significant (P < 0.05) in controlled diabetic patients. Statistically significant variability in diastolic BP (DBP) was also noted in controlled diabetic patients. Both systolic BP and DBPs were statistically significantly elevated after the administration of 2% lignocaine HCl. Conclusion: 2% lignocaine HCl with 1:200,000 epinephrine in type II diabetics and 2% lignocaine HCl should be used with caution in normotensive as well as type II controlled diabetic patients. |
| Databáze: | OpenAIRE |
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