Changes of inflammatory cytokines in vertebral compression fractures patients with percutaneous balloon kyphoplasty
| Autor: | Jian Zhang, Fengbin Sun, Hongbo Li, Weiwei Lu, Yanchun Xu |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Percutaneous business.industry General Medicine Balloon Compression (physics) Surgery Proinflammatory cytokine 03 medical and health sciences 0302 clinical medicine 030220 oncology & carcinogenesis medicine sense organs Neurology (clinical) business 030217 neurology & neurosurgery |
| Zdroj: | British Journal of Neurosurgery. :1-5 |
| ISSN: | 1360-046X 0268-8697 |
| Popis: | To explore the changes of a series of cytokines before and after percutaneous balloon kyphoplasty (PKP) and prognostic markers for response to PKP.From 1 January 2019 to 31 May 2019, all single-level lumbar osteoporotic vertebral compression fracture (OVCF) patients diagnosed by MRI who matched the inclusion and exclusion criteria were enrolled in this study. They were classified into the effective group and the ineffective group based on the outcome after PKP. The levels of a series of inflammatory factors and indices of spinal functions were obtained before and after PKP.A total of 72 patients were included in this study, 59 in the effective group and 13 in the ineffective group. The anterior height (AH) and posterior height (PH) were 77.3 ± 11.2% and 91.2 ± 9.3%, respectively, in the effective group after PKP, which were higher than that in the ineffective group (Our results demonstrated that PKP can reduce the serum levels of IL-6, IL-1β, and TNF-α, moreover, the IL-6, TNF-α, and AH were significant predictors of outcome. |
| Databáze: | OpenAIRE |
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