Synergism of lorazepam and electroconvulsive therapy in the treatment of catatonia
| Autor: | George Bush, Andrew Francis, Georgios Petrides, Krishna M. Divadeenam |
|---|---|
| Rok vydání: | 1997 |
| Předmět: |
Adult
Male Psychosis Adolescent Catatonia medicine.medical_treatment Lorazepam behavioral disciplines and activities Electroconvulsive therapy Pharmacotherapy mental disorders medicine Humans Combined Modality Therapy Anesthesia Prospective Studies Electroconvulsive Therapy GABA Modulators Biological Psychiatry Chemotherapy business.industry medicine.disease Clinical trial Female business medicine.drug |
| Zdroj: | Biological Psychiatry. 42:375-381 |
| ISSN: | 0006-3223 |
| DOI: | 10.1016/s0006-3223(96)00378-2 |
| Popis: | Electroconvulsive therapy (ECT) and lorazepam are effective treatments for catatonia. ECT combined with benzodiazepines has been associated with reduced efficacy and efficiency and therefore is not recommended in the routine practice of ECT. We report 5 prospectively identified cases of catatonia treated either sequentially or concurrently with lorazepam and ECT. In each case, the combination of lorazepam with ECT was superior to monotherapy. This apparent synergism, its possible mechanisms, and its implications for treating catatonia are discussed. |
| Databáze: | OpenAIRE |
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