Isolation and characterization of pre-rapamycin, the first macrocyclic intermediate in the biosynthesis of the immunosuppressant rapamycin by S. hygroscopicus
| Autor: | Sabine Gaisser, Matthew Alan Gregory, James Staunton, Hui Hong, Rachel E. Lill, Alison J. Weston, Rose Mary Sheridan, Isabelle Carletti, Peter F. Leadlay, Barrie Wilkinson, Huai-Lo Lee, Hrvoje Petković |
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| Rok vydání: | 2004 |
| Předmět: |
Sirolimus
Magnetic Resonance Spectroscopy biology Molecular Structure Stereoisomerism General Medicine General Chemistry Catalysis Gas Chromatography-Mass Spectrometry Streptomyces chemistry.chemical_compound Polyketide Pre-rapamycin Biosynthesis chemistry Biochemistry Genes Bacterial Polyketide synthase biology.protein Cloning Molecular Immunosuppressive Agents |
| Zdroj: | Angewandte Chemie (International ed. in English). 43(19) |
| ISSN: | 1433-7851 |
| Databáze: | OpenAIRE |
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