The Changing Role of Surgery in the Management of Rhabdomyosarcoma
| Autor: | Fitzgerald Rj, B. Connolly, F. Breatnach, Anthony Staines, A. O’Meara |
|---|---|
| Rok vydání: | 1992 |
| Předmět: |
Male
Reoperation Disease status medicine.medical_specialty medicine.medical_treatment Soft Tissue Neoplasms Disease Antineoplastic Combined Chemotherapy Protocols Rhabdomyosarcoma medicine Humans business.industry Infant Subtotal Resection medicine.disease Combined Modality Therapy Sick child Surgery Survival Rate Radiation therapy El Niño Child Preschool Pediatrics Perinatology and Child Health Female Presentation (obstetrics) business Follow-Up Studies |
| Zdroj: | Europe PubMed Central |
| ISSN: | 1439-359X 0939-7248 |
| Popis: | A retrospective analysis was performed of 56 patients presenting to Our Lady's Hospital for Sick Children, Crumlin, Dublin, Ireland, over a 25 year period with a diagnosis of rhabdomyosarcoma, in an effort to assess the changing role of surgery in the management of this disease. There were 38 males and 18 females; the age range at presentation was from birth to 13 years with a median of three years. Head and neck tumors occurred most frequently (23) followed by pelvic (14), paratesticular (6), extremities (6), gastrointestinal (4) and thoracic (3). Prior to 1971 there were no survivors while a doubling of survival has been observed within the past decade (31% to 63%). The minimum period of follow-up was four years. Surgical intervention ranged from total primary excision (20) to biopsy only (21) with total or subtotal resection performed electively in 15. Surgical evaluations, including examinations under anesthesia, staging laparotomy and second look laparotomy were also invaluable in assessing disease status. The incorporation of multiagent chemotherapy together with more selective use of radiotherapy has enabled a more conservative role to be adopted by the surgical oncologist thereby minimizing longterm sequelae. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|