Acute COVID-19 Infection in a Pediatric Patient with ROHHAD
| Autor: | Michael Avesar, Merrick Lopez, Daniel S. Udrea, Harsha K. Chandnani, Sonea Qureshi, Shamel Abd-Allah, Anthony Moretti |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
Mechanical ventilation Abdominal pain business.industry medicine.medical_treatment medicine.disease Pericardial effusion Hypoventilation Airway pressure release ventilation 03 medical and health sciences 030104 developmental biology 0302 clinical medicine Respiratory failure 030225 pediatrics Anesthesia Pediatrics Perinatology and Child Health ROHHAD medicine Autonomic dysregulation medicine.symptom business Genetics (clinical) |
| Zdroj: | J Pediatr Genet |
| Popis: | The novel coronavirus (severe acute respiratory syndrome coronavirus-2) has led to a global pandemic. In the adult population, coronavirus disease 2019 (COVID-19) has been found to cause multiorgan system damage with predicted long-term sequelae. We present a case of a 10-year-old boy with a history of ROHHAD (rapid-onset obesity with hypothalamic dysregulation, hypoventilation, and autonomic dysregulation) who presented with hypoxia, emesis, and abdominal pain. Imaging found bilateral ground glass opacities in the lungs and a pericardial effusion. Laboratory evaluation was concerning for elevated inflammatory markers. Remdesivir, hydroxychloroquine, and anticoagulation (heparin and enoxaparin) were utilized. The patient's severe respiratory failure was managed with conventional mechanical ventilation, inhaled nitric oxide, and airway pressure release ventilation. We hope that this report provides insight into the course and management of the severe acute pediatric COVID-19 patient, specifically with underlying comorbidities such as ROHHAD. Clinical trial registration is none. |
| Databáze: | OpenAIRE |
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