Tissue Engineering for Periodontal Ligament Regeneration: Biomechanical Specifications
| Autor: | Christophe Jeannin, Nina Attik, Brigitte Grosgogeat, K. Gritsch, Rémy Gauthier, Ana-Maria Trunfio-Sfarghiu |
|---|---|
| Přispěvatelé: | Laboratoire des Multimatériaux et Interfaces (LMI), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Faculté d’Odontologie, Université de Lyon-Université de Lyon, Laboratoire de Mécanique des Contacts et des Structures [Villeurbanne] (LaMCoS), Institut National des Sciences Appliquées de Lyon (INSA Lyon), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Université de Lyon-Institut National des Sciences Appliquées (INSA)-Centre National de la Recherche Scientifique (CNRS) |
| Rok vydání: | 2020 |
| Předmět: |
Periodontal tissue
Periodontal Ligament Biomedical Engineering FOS: Physical sciences 03 medical and health sciences 0302 clinical medicine stomatognathic system Tissue engineering Physiology (medical) Periodontal fiber Cyclic loading Medicine [PHYS.MECA.BIOM]Physics [physics]/Mechanics [physics]/Biomechanics [physics.med-ph] 030304 developmental biology Orthodontics 0303 health sciences Structural organization business.industry Regeneration (biology) Biomechanics Biomaterial 030206 dentistry Physics - Medical Physics Biomechanical Phenomena Medical Physics (physics.med-ph) business |
| Zdroj: | Journal of Biomechanical Engineering Journal of Biomechanical Engineering, American Society of Mechanical Engineers, 2021, 143 (3), ⟨10.1115/1.4048810⟩ |
| ISSN: | 0148-0731 |
| DOI: | 10.48550/arxiv.2012.14683 |
| Popis: | International audience; The periodontal biomechanical environment is very difficult to investigate. By the complex geometry and composition of the periodontal ligament, its mechanical behavior is very dependent on the type of loading (compressive vs. tensile loading; static vs. cyclic loading; uniaxial vs. multiaxial) and the location around the root (cervical, middle, or apical). These different aspects of the periodontal ligament make it difficult to develop a functional biomaterial to treat periodontal attachment due to periodontal diseases. This review aims to describe the structural and biomechanical properties of the periodontal ligament. Particular importance is placed in the close interrelationship that exists between structure and biomechanics: the periodontal ligament structural organization is specific to its biomechanical environment, and its biomechanical properties are specific to its structural arrangement. This balance between structure and biomechanics can be explained by a mechanosensitive periodontal cellular activity. These specifications have to be considered in the further tissue engineering strategies for the development of an efficient biomaterial for periodontal tissues regeneration. |
| Databáze: | OpenAIRE |
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