Methyldopa-Induced Syndrome of Inappropriate Antidiuretic Hormone Secretion and Bone Marrow Granulomatosis

Autor: Yakov Varkel, Tamar Shkolnik, David Nusem, Andrei Braester
Rok vydání: 1988
Předmět:
Zdroj: Drug Intelligence & Clinical Pharmacy. 22:700-701
ISSN: 0012-6578
DOI: 10.1177/106002808802200911
Popis: A case of an elderly man who developed severe hyponatremia and bone marrow granulomatosis while taking methyldopa is described. The hyponatremia was found to be due to the syndrome of inappropriate antidiuretic hormone secretion (SIADH). Bone marrow biopsy revealed granulomas. A MEDLINE search of the English literature was done, yielding only one previous report of methyldopa-induced bone marrow granulomatosis and no previous reports of methyldopa-induced SIADH.
Databáze: OpenAIRE