Effect of increased BMI and obesity on the outcome of COVID-19 adult patients: A systematic review and meta-analysis
| Autor: | Hendarsyah Suryadinata, Aga Purwiga, Ferdy Ferdian, Arto Yuwono Soeroto, Iceu Dimas Kulsum, Prayudi Santoso, Nanny N M Soetedjo |
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| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty Endocrinology Diabetes and Metabolism medicine.medical_treatment Overweight Severity of Illness Index Article 03 medical and health sciences Sex Factors 0302 clinical medicine Internal medicine Diabetes mellitus Internal Medicine Humans Medicine Obesity 030212 general & internal medicine Risk factor Body mass index Mechanical ventilation Respiratory Distress Syndrome SARS-CoV-2 business.industry Age Factors General Medicine Odds ratio medicine.disease Respiration Artificial Hospitalization Intensive Care Units 030104 developmental biology Diabetes Mellitus Type 2 Meta-analysis Hypertension medicine.symptom Covid-19 business Poor outcome |
| Zdroj: | Diabetes & Metabolic Syndrome Diabetes & Metabolic Syndrome: Clinical Research & Reviews |
| ISSN: | 1871-4021 |
| DOI: | 10.1016/j.dsx.2020.09.029 |
| Popis: | Background and aims Corona virus diseases 2019 (COVID-19) pandemic spread rapidly. Growing evidences that overweight and obesity which extent nearly a third of the world population were associated with severe COVID-19. This study aimed to explore the association and risk of increased BMI and obesity with composite poor outcome in COVID-19 adult patients. Methods We conducted a systematic literature search from PubMed and Embase database. We included all original research articles in COVID-19 adult patients and obesity based on classification of Body Mass Index (BMI) and composite poor outcome which consist of ICU admission, ARDS, severe COVID-19, use of mechanical ventilation, hospital admission, and mortality. Results Sixteen studies were included in meta-analysis with 9 studies presented BMI as continuous outcome and 10 studies presented BMI as dichotomous outcome (cut-off ≥30 kg/m2). COVID-19 patients with composite poor outcome had higher BMI with mean difference 1.12 (95% CI, 0.67–1.57, P Highlights • Adult COVID-19 patients with poor outcome had higher body mass index (BMI) with mean difference of 1.12 kg/m2 (P |
| Databáze: | OpenAIRE |
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