The challenges of diagnosing diabetes in childhood
Autor: | Giuseppe Lippi, Martina Montagnana, Claudia Lo Cascio, Mairi Pucci, Marco Benati |
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Jazyk: | angličtina |
Rok vydání: | 2021 |
Předmět: |
Pediatrics
medicine.medical_specialty endocrine system diseases Clinical Biochemistry Medicine (miscellaneous) 030209 endocrinology & metabolism 030204 cardiovascular system & hematology MODY children diabetes mellitus genetics hyperglycemia 03 medical and health sciences 0302 clinical medicine children Diabetes mellitus medicine Blood test genetics American diabetes association Type 1 diabetes medicine.diagnostic_test business.industry Health Policy Biochemistry (medical) Public Health Environmental and Occupational Health nutritional and metabolic diseases Type 2 Diabetes Mellitus medicine.disease MODY diabetes mellitus hyperglycemia Differential diagnosis business |
Popis: | Diabetes is one of the most prevalent diseases worldwide, whereby type 1 diabetes mellitus (T1DM) alone involves nearly 15 million patients. Although T1DM and type 2 diabetes mellitus (T2DM) are the most common types, there are other forms of diabetes which may remain often under-diagnosed, or that can be misdiagnosed as being T1DM or T2DM. After an initial diagnostic step, the differential diagnosis among T1DM, T2DM, Maturity-Onset Diabetes of the Young (MODY) and others forms has important implication for both therapeutic and behavioral decisions. Although the criteria used for diagnosing diabetes mellitus are well defined by the guidelines of the American Diabetes Association (ADA), no clear indications are provided on the optimal approach to be followed for classifying diabetes, especially in children. In this circumstance, both routine and genetic blood test may play a pivotal role. Therefore, the purpose of this article is to provide, through a narrative literature review, some elements that may aid accurate diagnosis and classification of diabetes in children and young people. |
Databáze: | OpenAIRE |
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