Discomfort during bronchoscopy performed after endobronchial intubation with fentanyl and midazolam: a prospective study
| Autor: | Katsuyuki Kiura, Nagio Takigawa, Masahiro Tabata, Katsuyuki Hotta, Hirohisa Kano, Daisuke Minami, Akiko Sato, Eiki Ichihara, Mitsune Tanimoto, Takashi Ninomiya, Toshio Kubo, Kadoaki Ohashi |
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| Rok vydání: | 2017 |
| Předmět: |
Adult
Male Cancer Research medicine.medical_specialty Visual analogue scale Midazolam Sedation Fentanyl 03 medical and health sciences 0302 clinical medicine Patient satisfaction Japan Bronchoscopy Surveys and Questionnaires medicine Humans Radiology Nuclear Medicine and imaging Prospective Studies Prospective cohort study Aged Aged 80 and over medicine.diagnostic_test business.industry Hemodynamics General Medicine Middle Aged Surgery Clinical trial 030228 respiratory system Oncology 030220 oncology & carcinogenesis Anesthesia Female medicine.symptom Intubation business medicine.drug |
| Zdroj: | Japanese Journal of Clinical Oncology. 47:434-437 |
| ISSN: | 1465-3621 0368-2811 |
| Popis: | Objective Although endobronchial intubation during a bronchoscopic examination is useful for invasive procedures, it is not routine practice in Japan. The present study evaluated discomfort due to endobronchial intubation using fentanyl and midazolam sedation during bronchoscopy. Methods Thirty-nine patients were enrolled prospectively from November 2014 to September 2015 at Okayama University Hospital. Fentanyl (20 µg) was administered to the patients just before endobronchial intubation, and fentanyl (10 µg) and midazolam (1 mg) were added as needed during the procedure. A questionnaire survey was administered 2 h after the examination. In the questionnaire, patient satisfaction was scored using a visual analog scale as follows: excellent (1 point), good (2 points), normal (3 points), uncomfortable (4 points) and very uncomfortable (5 points). An additional question ('Do you remember the bronchoscopic examination?') was also asked. Predefined parameters (blood pressure, heart rate, oxygen saturation and complications) were recorded. Results The enrolled patients included 22 males and 17 females; their median age was 70 (range: 28-88) years. The patients received a mean dose of 47.9 µg of fentanyl (range: 30-90 µg) and 2.79 mg of midazolam (range: 1-7 mg). In total, 28 patients (71.7%) agreed to undergo a second bronchoscopic examination; the mean levels of discomfort and for the re-examination were 2.07 points each. About 41% of the patients remembered the bronchoscopic examination. No severe complications were reported. Conclusion Endobronchial intubation using fentanyl and midazolam sedation during an invasive bronchoscopic procedure might be recommended. Clinical trial registration UMIN000015578 in the UMIN Clinical Trials Registry. |
| Databáze: | OpenAIRE |
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