Optic Neuropathy Due to Chronic Lymphocytic Leukemia: the First Manifestation of the Disease
| Autor: | João Paulo Cunha, Diogo Hipolito-Fernandes, Joana Tavares Ferreira, Diogo Maleita, Nuno Moura-Coelho, Rita Serras Pereira |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Pathology
medicine.medical_specialty genetic structures Chronic lymphocytic leukemia Optic Neuropathy Central nervous system Case Report Disease Optic neuropathy 03 medical and health sciences Optic nerve infiltration 0302 clinical medicine Cerebrospinal fluid lcsh:Ophthalmology immune system diseases hemic and lymphatic diseases medicine Chronic Lymphocytic Leukemia business.industry Optic Nerve Infiltration medicine.disease eye diseases Ophthalmology medicine.anatomical_structure CHLC OFT lcsh:RE1-994 030221 ophthalmology & optometry Optic nerve sense organs Complication business Infiltration (medical) 030217 neurology & neurosurgery |
| Zdroj: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) Agência para a Sociedade do Conhecimento (UMIC)-FCT-Sociedade da Informação instacron:RCAAP American Journal of Ophthalmology Case Reports, Vol 18, Iss, Pp-(2020) American Journal of Ophthalmology Case Reports |
| Popis: | Purpose: Chronic lymphocytic leukemia (CLL) is the most common lymphoproliferative disorder in the western world. The involvement of the central nervous system (CNS) or the optic nerve in CLL, however, is rare. We report a case of a previously untreated patient with CLL whose first manifestation of the disease was a progressive visual loss caused by optic neuropathy. Observations: Clinical manifestations, optical coherence tomography (OCT), and automated visual fields pointed to the diagnosis of neuropathy. Leukemic involvement of the CNS was confirmed after cells suggestive of CLL were found by cerebrospinal fluid analysis. Optic nerve infiltration is thought to be the cause of this optic neuropathy, and the clinical course and treatment are described herein. Conclusions: When readily diagnosed, optic nerve infiltration is a rare, yet manageable complication of CLL. info:eu-repo/semantics/publishedVersion |
| Databáze: | OpenAIRE |
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