Haemolytic-uraemic syndrome with bacteraemia caused by a new hybrid Escherichia coli pathotype
| Autor: | Patricia Mariani-Kurkdjian, L. Boggini, D. Perez, C. Lemaître, T. Kwon, Philippe Bidet, Stéphane Bonacorsi |
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| Rok vydání: | 2014 |
| Předmět: |
Serotype
bacteraemia Virulence Biology bacterial infections and mycoses medicine.disease_cause Microbiology Virology lcsh:Infectious and parasitic diseases 3. Good health ColV plasmid Infectious Diseases Plasmid New Microbes in Humans - New Resistant Microbes in Humans extraintestinal virulence factors Shiga toxin producing Shiga toxin-producing Escherichia coli Antibiotic therapy medicine haemolytic–uraemic syndrome lcsh:RC109-216 Haemolytic-uraemic syndrome Gene Escherichia coli |
| Zdroj: | New Microbes and New Infections New Microbes and New Infections, Vol 2, Iss 4, Pp 127-131 (2014) |
| ISSN: | 2052-2975 |
| DOI: | 10.1002/nmi2.49 |
| Popis: | We describe a new atypical Shiga-toxin-producing Escherichia coli (STEC) responsible for a severe episode of haemolytic–uraemic syndrome in an adult with a relapse associated with bacteraemia. This STECs train of serotype O80:H2 harboured stx2c and stx2d gene subtypes, the rare eae ɛ variant and a ColV plasmid with a conserved virulence plasmidic region involved in virulence of human and avian extraintestinal pathogenic E. coli. This atypical hybrid pathotype, which represents a new threat, is a further demonstration that STEC may be a recipient for extraintestinal virulence factors and raises again the question of antibiotic therapy during STEC infection. |
| Databáze: | OpenAIRE |
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