Termination of Repeat Testing in Chemical Laboratories Based on Practice Guidelines: Examining the Effect of Rule-Based Repeat Testing in a Transplantation Center
| Autor: | Sahand Mohammadzadeh, Neda Soleimani, Tayebeh Hosseyni, Samira khajeh, Arezoo Arabzadeh, Mahsa Farhadi, Reza Ghahramani, Mohammad Javad Esmaeili, Azadeh Hafezi, Fatemeh Ghodsi, Amir Azadi |
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| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Article Subject Bilirubin General Chemical Engineering 030204 cardiovascular system & hematology Gastroenterology Analytical Chemistry 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Total iron-binding capacity Lactate dehydrogenase Internal medicine medicine Instrumentation Blood urea nitrogen Creatinine QD71-142 medicine.diagnostic_test biology business.industry Albumin Computer Science Applications Transplantation chemistry 030220 oncology & carcinogenesis biology.protein Creatine kinase business Research Article |
| Zdroj: | Journal of Analytical Methods in Chemistry Journal of Analytical Methods in Chemistry, Vol 2021 (2021) |
| ISSN: | 2090-8873 2090-8865 |
| Popis: | Background. Although the automation of instruments has reduced the variability of results and errors of analysis, in some laboratories, repeating a test to confirm its accuracy is still performed for critical and noncritical results. However, the importance of repeat testing is not well established yet, and there are no clear criteria for repeating a test. Materials and Methods. In this cross-sectional study, all repeated tests for 26 biochemical analytes (i.e., albumin, alkaline phosphatase (ALP), alanine aminotransferase (ALT), amylase, aspartate aminotransferase (AST), bilirubin total (BT), bilirubin direct (BD), blood urea nitrogen (BUN), calcium, chloride (Cl), cholesterol total (CholT), creatine kinase (CK), creatinine (Cr), glucose, gamma-glutamyl transferase (GGT), high-density lipoprotein-cholesterol (HDL-c), iron, lactate dehydrogenase (LDH), LDL-c, lipase, magnesium (Mg), phosphorus (Ph), protein total (ProtT), total iron binding capacity (TIBC), triglyceride (TG), and uric acid) were assessed in both critical and noncritical ranges over two consecutive months (routine subjective test repeats in the first month and rule-based repeats in the second month). To determine the usefulness of test repeats, differences between the initial and verified results were compared with the allowable bias, and repeat testing was considered necessary if it exceeded the allowable bias range. All causes of repeat testing, including linearity flags, delta checks, clinically significant values, and critical values, were also documented. All data, including the cause of repeats, initial and verified results, time, and costs in the two consecutive months, were transferred to Microsoft Excel for analysis. For comparison of data between the months, Student’s t-test was used. Results. A total of 7714 repeat tests were performed over two consecutive months. Although a significant decline (38%) was found in repeated tests in the second month ( P |
| Databáze: | OpenAIRE |
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