Histologic and skeletal abnormalities in benzo(a)pyrene-treated rainbow trout alevins
Autor: | Harold W. Puffer, James B. Hannaht, Marsha L. Landolt, Jo Ellen Hose |
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Rok vydání: | 1984 |
Předmět: |
medicine.medical_specialty
animal structures Trout Health Toxicology and Mutagenesis Toxicology Microphthalmia chemistry.chemical_compound Internal medicine medicine Benzo(a)pyrene Animals Microphthalmos Tissue Distribution Kyphosis Salmo biology Karyorrhexis Histology General Medicine medicine.disease biology.organism_classification Pollution Endocrinology medicine.anatomical_structure chemistry Toxicity Rainbow trout Nervous System Diseases Vertebral column Salmonidae |
Zdroj: | Archives of environmental contamination and toxicology. 13(6) |
ISSN: | 0090-4341 |
Popis: | Histological and skeletal examinations were performed on rainbow trout (Salmo gairdneri Richardson) alevins reared in 0.00, 0.08, 0.21, 0.39, 1.48, 2.40 or 2.99 ng/ml aqueous benzo(a)pyrene (BaP). Nuclear pycnosis and karyorrhexis were most common in neuroectodermal and mesodermal derivatives and in liver of BaP-treated alevins. Microphthalmia was observed in 17% of the test fish and was frequently associated with a patent optic fissure. Depressed mitotic rates in the retina and brain (but not liver) were observed in alevins reared in 0.21 to 1.48 ng/ml aqueous BaP. Test alevins had a significantly higher incidence of skeletal malformations in the skull and vertebral column, and abnormalities of vertebral arcualia often corresponded to areas of kyphoscoliotic flexures. |
Databáze: | OpenAIRE |
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