Malfunctioning sufentanil intrathecal pain pump: a case report
| Autor: | Lindsay R Hunter Guevara, Jason S. Eldrige, Laura Matzke Bitterman, Matthew J. Pingree, Wayne T. Nicholson, Anna M. Branstad, Lindsay L. Warner |
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| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Drug
Sufentanil media_common.quotation_subject IDDS lcsh:Medicine Case Report 03 medical and health sciences 0302 clinical medicine Pharmacokinetics 030202 anesthesiology Surgical oncology Chronic pain management Medicine Dosing media_common business.industry lcsh:R Chronic pain General Medicine Pain pump medicine.disease Pain management Opioid Anesthesia Drug delivery business 030217 neurology & neurosurgery Intrathecal opioid medicine.drug |
| Zdroj: | Journal of Medical Case Reports, Vol 14, Iss 1, Pp 1-4 (2020) Journal of Medical Case Reports |
| ISSN: | 1752-1947 |
| Popis: | Background Sufentanil is a potent opioid uncommonly used to manage pain and is rarely administered via an intrathecal pain pump system. Case presentation This case illustrates the use of intrathecal sufentanil in a 50-year-old Caucasian man for the management of chronic pain; however, the intrathecal drug delivery system experienced a malfunction which led to 1/100th output of the correct dosage. Interesting aspects of this case report include the uncommon choice of sufentanil use for an intrathecal drug delivery system, as well as the unusual pharmacokinetics of this drug. Specifically, this patient did not experience the major withdrawal that would be expected given significant under dosing of opioid, and this may be explained by the lipophilicity and context-sensitive half-times of sufentanil. Conclusions Because of the absence of a clinically significant withdrawal in this case report, clinicians must be aware of relevant pharmacokinetic properties and unusual intrathecal drug delivery system technologies that influence a patient’s response when device malfunction occurs. |
| Databáze: | OpenAIRE |
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