Synthesis of Osteoconductive Organic—Inorganic Nanohybrids through Modification of Chitin with Alkoxysilane and Calcium Chloride
| Autor: | Chikara Ohtsuki, Masahiro Ashizuka, Toshiki Miyazaki |
|---|---|
| Rok vydání: | 2007 |
| Předmět: |
Ceramics
Materials science Surface Properties Simulated body fluid 0206 medical engineering Inorganic chemistry Biomedical Engineering chemistry.chemical_element Chitin 02 engineering and technology In Vitro Techniques Calcium Apatite Biomaterials Calcium Chloride chemistry.chemical_compound Apatites Materials Testing Spectroscopy Fourier Transform Infrared Organic inorganic chemistry.chemical_classification Polymer Silanes 021001 nanoscience & nanotechnology 020601 biomedical engineering Body Fluids Nanostructures Silanol chemistry Chemical engineering visual_art Bone Substitutes Microscopy Electron Scanning visual_art.visual_art_medium 0210 nano-technology |
| Zdroj: | Journal of Biomaterials Applications. 22:71-81 |
| ISSN: | 1530-8022 0885-3282 |
| DOI: | 10.1177/0885328206070447 |
| Popis: | The so-called bioactive ceramics have been attractive because they spontaneously bond to living bone. Organic—inorganic hybrids consisting of organic polymers and the essential constituents of the bioactive ceramics, i.e., silanol (Si—OH) group and calcium ions (Ca2+), are useful as novel bone substitutes, owing to bioactivity and high flexibility. In the present study, organic—inorganic hybrids are synthesized from chitin by modification with glycidoxypropyltrimethoxysilane (GPS) and calcium chloride (CaCl2). Their apatite-forming ability is examined in a simulated body fluid (SBF). The prepared hybrids form apatite on their surfaces in SBF within 7 days. |
| Databáze: | OpenAIRE |
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