Effects of Labisia pumila on oxidative stress in rat model of post-menopausal osteoporosis
| Autor: | Nicolaas Budhiparama, Bambang Setiawan, Nelly Mariati, Noorhamdani Noorhamdani, Nurdiana Nurdiana, Zairin Noor |
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| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty Antioxidant Ovariectomy medicine.medical_treatment Lipid peroxidation Osteoporosis lcsh:Medicine Plant Science medicine.disease_cause Antioxidants Superoxide dismutase 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Internal medicine Oxidative damage medicine General Veterinary biology business.industry lcsh:R Obstetrics and Gynecology Labisia pumila Malondialdehyde biology.organism_classification medicine.disease 030104 developmental biology Endocrinology Reproductive Medicine chemistry Oxidative stress Ovariectomized rat biology.protein Animal Science and Zoology business 030217 neurology & neurosurgery |
| Zdroj: | Asian Pacific Journal of Reproduction, Vol 5, Iss 5, Pp 391-394 (2016) |
| ISSN: | 2305-0500 |
| Popis: | Objective: To analyze the effects of Labisia pumila (L. pumila) extract on the markers of oxidative stress in ovariectomized rats. Methods: Twenty-five female Wistar rats were divided into five treatment groups (n = 5): the control group, the ovariectomized group, the ovariectomized group treated with L. pumila extract of various doses (10 mg/kg, 20 mg/kg, and 40 mg/kg). L. pumila extract was administered daily for 8 weeks. Results: The levels of malondialdehyde and superoxide dismutase (SOD) were subjected to spectrophotometric analysis. Serum levels of malondialdehyde and SOD were significantly higher in the group of rat model of post-menopausal osteoporosis than that of the control group (P |
| Databáze: | OpenAIRE |
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