Endovascular reperfusion of M2 occlusions in acute ischemic stroke reduced disability and mortality: ETIS Registry results
| Autor: | Bertrand Lapergue, Gaultier Marnat, Maxime Gauberti, Arturo Consoli, Stephane Vannier, François Eugène, Romain Bourcier, Frédéric Bourdain, Suzana Saleme, Caroline Arquizan, Marion Boulanger, Sébastien Richard, Louis Veunac, Ozlem Ozkul-Wermester, Anthony Le Bras, Benjamin Gory, Cyril Dargazanli, Jean-Christophe Gentric, Stephanos Nikolaos Finitsis, Mohammad Anadani, C. Papagiannaki, Valérie Wolff, Christophe Cognard, Benjamin Maïer, Laurent Spelle, Christian Denier, Patricio Muszynski, Sarah Evain, Francisco Macian, Guillaume Turc, Raoul Pop, Raphaël Blanc, Frédéric Clarençon, Alain Viguier, Serge Timsit, Olivier Naggara, Igor Sibon, Charlotte Rosso |
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| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
medicine.medical_treatment Brain Ischemia Modified Rankin Scale Internal medicine medicine Humans Favorable outcome Prospective Studies Registries Endovascular treatment Stroke Acute ischemic stroke Ischemic Stroke Thrombectomy business.industry Cerebral infarction Stroke scale Endovascular Procedures General Medicine Thrombolysis medicine.disease Treatment Outcome Reperfusion Cardiology Surgery Neurology (clinical) business |
| Zdroj: | Journal of neurointerventional surgery. 14(5) |
| ISSN: | 1759-8486 |
| Popis: | BackgroundThe predictors of successful reperfusion and the effect of reperfusion after endovascular treatment (EVT) for M2 occlusions have not been well studied. We aimed to identify predictors of successful reperfusion and the effect of reperfusion on outcomes of EVT for M2 occlusions in current practice.MethodsPatients with acute ischemic stroke due to isolated M2 occlusions who were enrolled in the prospective multicenter Endovascular Treatment in Ischemic Stroke (ETIS) Registry in France between January 2015 and March 2020 were included. The primary outcome was a favorable outcome, defined as modified Rankin Scale (mRS) score of 0–2 at 90 days. Successful reperfusion was defined as an improvement of ≥1 points in the modified Thrombolysis In Cerebral Infarction score between the first and the last intracranial angiogram.ResultsA total of 458 patients were included (median National Institutes of Health Stroke Scale (NIHSS) score 14; 61.4% received prior intravenous thrombolysis). Compared with the non-reperfused patients, reperfused patients had an increased rate of excellent outcome (OR 2.3, 95% CI 0.98 to 5.36; p=0.053), favorable outcome (OR 2.79, 95% CI 1.31 to 5.93; p=0.007), and reduced 90-day mortality (OR 0.39, 95% CI 0.19 to 0.79; pConclusionsSuccessful reperfusion of M2 occlusions reduced disability and mortality. However, safety is a concern, especially if the procedure failed. |
| Databáze: | OpenAIRE |
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