Lymphocytosis Response in Mice and Its Relation to Thymus and Adrenal
Autor: | R. F. Buffett, Donald Metcalf |
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Rok vydání: | 1957 |
Předmět: |
Thymus extract
medicine.medical_specialty Lymphocytosis business.industry medicine.medical_treatment Adrenalectomy Spleen Thymus Gland medicine.disease General Biochemistry Genetics and Molecular Biology Thymectomy Mice Leukemia Endocrinology medicine.anatomical_structure Inbred strain Internal medicine Adrenal Glands Immunology medicine Animals medicine.symptom business Lymph node |
Zdroj: | Experimental Biology and Medicine. 95:576-579 |
ISSN: | 1535-3699 1535-3702 |
DOI: | 10.3181/00379727-95-23296 |
Popis: | Summary(1) Mice of certain inbred strains (C57Bl, Rf, and LAF1), when bled daily from tail veins, developed a prompt and persistent lymphocytosis. (2) High leukemia strains AkR and C58 did not show this response. (3) Thymectomy prevented this response but lymphocytosis was produced in thymectomized mice by injection of cell-free thymus extracts. Lymph node and spleen extracts were ineffective. (4) Adrenalectomy did not affect the lymphocytosis response. |
Databáze: | OpenAIRE |
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