CRISPR/Cas9-edited NSG mice as PDX models of human leukemia to address the role of niche-derived SPARC

Autor:	A Contreras, Ewelina Czlonka, Uwe Platzbecker, Aleksandra Nevmerzhitskaya, E Bergonzani, Irene Tirado-Gonzalez, F. van der Hoeven, Jean-Pierre Bourquin, U Kloz, Abdelrahman Mahmoud, Irmela Jeremias, H Medyouf, Devona Soetopo
Přispěvatelé:	University of Zurich
Jazyk:	angličtina
Rok vydání:	2018
Předmět:	0301 basic medicine CRISPR-Cas9 genome editing endocrine system Cancer Research Human leukemia Niche 2720 Hematology 610 Medicine & health Computational biology Biology digestive system Article Mice 03 medical and health sciences 0302 clinical medicine Mice Inbred NOD Tumor Microenvironment Animals Humans CRISPR Leukaemia Clustered Regularly Interspaced Short Palindromic Repeats Osteonectin 1306 Cancer Research Cancer models Cancer Glycoproteins Gene Editing Leukemia Cas9 Disease progression Correction Hematology Mice Inbred C57BL 030104 developmental biology Oncology 10036 Medical Clinic Hematologic Neoplasms 030220 oncology & carcinogenesis Disease Progression Heterografts 2730 Oncology CRISPR-Cas Systems hormones hormone substitutes and hormone antagonists Biotechnology
Zdroj:	Leukemia 32, 1048-1051 (2018) Leukemia
Popis:	CRISPR/Cas9 edited NSG mice as PDX models of human leukemia to address the role of niche-derived SPARC
Databáze:	OpenAIRE
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