| Autor: |
Joseph M. Beechem, Gary Geiss, John S. Lyssand, Hiromi Sato, Saskia Ilcisin, Chi Q. Phan, Felicia New, Daniel Newhouse, Aric B.E. Rininger, Mark Conner, Giang T. Ong, Alyssa B. Rosenbloom, Shilah A. Bonnett |
| Rok vydání: |
2023 |
| DOI: |
10.1158/2767-9764.22744303 |
| Popis: |
Spatial proteogenomics across mouse tissue types. High-plex SPG characterization of mouse tissues with matched circular ROIs. FFPE sections were stained with GeoMx Mouse WTA (RNA control), 15-stacked GeoMx Mouse Protein Modules (137-plex; protein control), or both analytes simultaneously with the SPG workflow. A, Concordance and representative images of mouse tissue used in the assessment of the SPG versus the respective RNA (top) and protein (bottom) control. Unsupervised hierarchical clustering of top 400 expressing RNA targets with an SNR ≥ 4 (B) and detected protein targets (SNR ≥ 3; C) across all tissue types. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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