Serious Mental Illness in Heavy Drinkers Is Associated with Poor Treatment Outcomes in Outpatients with Co-occurring Disorders
| Autor: | Sterling McPherson, Jordan Skalisky, Oladunni Oluwoye, Debra Srebnik, Michael G. McDonell, Richard K. Ries, John M. Roll, Katherine Hirchak, Emily Leickly |
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| Rok vydání: | 2018 |
| Předmět: |
medicine.medical_specialty
business.industry Alcohol dependence Contingency management Mental illness medicine.disease Article 030227 psychiatry 03 medical and health sciences Psychiatry and Mental health chemistry.chemical_compound Health psychology 0302 clinical medicine Ethyl glucuronide chemistry mental disorders medicine 030212 general & internal medicine Psychiatry business Generalized estimating equation Depression (differential diagnoses) Alcohol Abstinence |
| Zdroj: | International journal of mental health and addiction. 16(3) |
| ISSN: | 1557-1874 |
| Popis: | The objective of this study was to determine whether the interaction between type of serious mental illness (SMI) and pre-treatment drinking severity, assessed by ethyl glucuronide (EtG), predicts EtG-positive urine samples submitted during treatment in outpatients with co-occurring alcohol dependence and SMI. Seventy-nine participants were randomized to treatment-as-usual or treatment-as-usual and contingency management (CM) targeting alcohol abstinence. Generalized estimating equations were used to assess the interaction of pre-treatment drinking (heavy drinking or light drinking) and SMI diagnosis (major depression, bipolar, or schizophrenia-spectrum disorders) across a 12-week treatment period. In the overall sample, the interaction of drinking severity and SMI diagnosis (p = 0.006) was associated with alcohol abstinence. Exploratory analyses of the interaction term among participants randomized to CM (n = 40; p = 0.008) were associated with alcohol abstinence during CM. Type of SMI diagnosis was associated with treatment outcomes in individuals who engaged in heavy drinking, but not light drinking, prior to treatment. |
| Databáze: | OpenAIRE |
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