Central Giant Cell Lesion
| Autor: | James C. Valentine, Brenda L. Nelson |
|---|---|
| Rok vydání: | 2011 |
| Předmět: |
Pathology
medicine.medical_specialty Osteitis fibrosa cystica Osteoclasts Giant Cells Sine qua none Radiology-Pathology Pathology and Forensic Medicine Diagnosis Differential Lesion Young Adult Granuloma Giant Cell medicine Humans Giant Cell Tumor of Bone business.industry Hyperparathyroidism Cell Differentiation medicine.disease Radiography Mandibular Neoplasms Brown tumor Peripheral giant-cell granuloma Oncology Otorhinolaryngology Giant cell Granuloma Female medicine.symptom Differential diagnosis business Giant-cell tumor of bone |
| Zdroj: | Head and Neck Pathology. 5:385-388 |
| ISSN: | 1936-0568 1936-055X |
| DOI: | 10.1007/s12105-011-0297-4 |
| Popis: | A classic case of central giant cell lesion (CGCL) is presented with emphasis on clinical, radiologic, and histologic features. The differential is discussed including peripheral giant cell granuloma, brown tumor of hyperparathyroidism, and giant cell tumor of bone. The molecular pathway of osteoclastogenesis is selectively reviewed and applied to suggest possible etiologies of the giant cell lesions. CGCL syndromes and treatment are also discussed. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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