Impact of Bariatric Surgery on Long-term Cardiovascular Risk: Comparative Effectiveness of Different Surgical Procedures
| Autor: | Castro Oliveira, SC, Neves, JS, Souteiro, P, Pedro, J, Magalhaes, D, Guerreiro, V, Bettencourt Silva, R, Costa, MM, Varela, A, Barroso, I, Freitas, P, Carvalho, D, Correia, Flora |
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| Přispěvatelé: | Faculdade de Ciências da Nutrição e Alimentação, Faculdade de Medicina, Instituto de Saúde Pública da Universidade do Porto |
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Adult
Male medicine.medical_specialty Sleeve gastrectomy Gastric bypass Endocrinology Diabetes and Metabolism medicine.medical_treatment Gastric Bypass Framingham Risk Score Bariatric Surgery Gastrectomy Risk Factors Weight loss Adjustable gastric band Weight Loss medicine Humans Obesity Longitudinal Studies Postoperative Period CVD risk Retrospective Studies Bariatric surgery Nutrition and Dietetics Portugal business.industry Health sciences Medical and Health sciences Ciências médicas e da saúde Middle Aged Surgical procedures medicine.disease Obesity Morbid Surgery Treatment Outcome Cardiovascular Diseases Heart Disease Risk Factors Medical and Health sciences Female Observational study Ciências da Saúde Ciências médicas e da saúde medicine.symptom business Follow-Up Studies |
| Zdroj: | Repositório Científico de Acesso Aberto de Portugal Repositório Científico de Acesso Aberto de Portugal (RCAAP) instacron:RCAAP |
| Popis: | Introduction Several reports highlight bariatric surgery as an efficient and long-lasting strategy for weight loss. Herein, we aimed to evaluate the impact of bariatric surgery on 10-year cardiovascular disease (CVD) risk and to compare the effectiveness of different surgical procedures, employing the Framingham Risk Score (FRS). Methods Retrospective longitudinal observational study of patients undergoing bariatric surgery. Data was assessed preoperatively and during a 4-year follow-up period. Results We evaluated 1449 individuals, 85.2% female, age of 42.4 +/- 10.6 years, and preoperative BMI of 44.3 +/- 5.8 kg/m(2); 58.0% underwent Roux-en-Y gastric bypass (RYGB), 23.4% sleeve gastrectomy (SG), and 18.6% adjustable gastric band (AGB). The 10-year CVD risk decreased 43.6% in the first postoperative year. The decrease in FRS was more pronounced in the RYGB group (50.5% in the first postoperative year) (p < 0.001). Although there was a subsequent slight increase in FRS during the follow-up period, the cardiovascular benefits were maintained when compared with baseline. For all surgical procedures, CVD risk showed a quadratic trend with a J-shaped curve. A negative interaction between the RYGB group CVD risk and time was observed (beta = - 0.072 (95% CI, - 0.109; - 0.035)). In the RYGB group, FRS decreased more when compared with the SG and AGB groups and, from the second postoperative year onwards, increased more slowly, regardless of gender. The SG group showed similar trend as that of the AGB (beta = - 0.002 (95% CI, - 0.049; 0.053)). Conclusion Our study showed a significant reduction of 10-year CVD risk after bariatric surgery. This decrease was more pronounced in the first postoperative year, and RYGB was the procedure with the greatest decrease of the 10-year CVD risk. |
| Databáze: | OpenAIRE |
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