Randomised clinical trial: comparison of acceptability, patient tolerance, cardiac stress and endoscopic views in transnasal and transoral endoscopy under local anaesthetic

Autor: J. N. Plevris, Peter C. Hayes, S. Inglis, Norma C. McAvoy, E. Falconer, Colin M. Graham, Efstratios Alexandridis
Rok vydání: 2014
Předmět:
Zdroj: Alimentary Pharmacology & Therapeutics.
ISSN: 0269-2813
DOI: 10.1111/apt.12866
Popis: Summary Background Transnasal endoscopy (TNE) with ultrathin endoscopes has been advocated as an attractive alternative, for diagnostic upper endoscopy. Aim To assess tolerability, acceptability and quality of TNE, in comparison with standard upper endoscopy (SOGD, standard oesophago-gastro-duodenoscopy) under local anaesthetic. Methods We prospectively recruited 157 patients (83 females/74 males) mean age 57 years. The Fujinon EG530N (5.9 mm) and EG530WR (9.4 mm) endoscopes were used. The endoscopist and all patients completed detailed questionnaires regarding tolerability, acceptance and quality of endoscopy using standard visual analogue scales (VAS). Oxygen saturation (SaO2), heart rate (HR) and systolic blood pressure (SBP) were recorded. Quality of biopsies was evaluated. Results Analysis included 161 procedures (TNE:79, SOGD:82) with duodenal intubation achieved in all patients. VAS scores for patient comfort were significantly better in the TNE group (7.3 vs. 5.3 respectively, P
Databáze: OpenAIRE