Effects of Bleeding on Electrolyte Excretion and on Glomerular Filtration

Autor: William N. Viar, T. R. Harrison, T. A. Lombardo, Seymour Eisenberg, B. B. Oliver, E. E. Eddleman
Rok vydání: 1951
Předmět:
Zdroj: Circulation. 3:260-270
ISSN: 1524-4539
0009-7322
DOI: 10.1161/01.cir.3.2.260
Popis: Removal of small amounts of blood from sitting subjects caused reduction of sodium excretion without alterations in creatinine clearance, or in apparent cardiac output (electrokymographic method). This reduction could be prevented by compression of the neck. The experiments support the concept of an homeostatic central mechanism which regulates the volume of extracellular fluid by altering sodium excretion. If such a mechanism exists it is apparently activated by changes in the volume of body fluids rather than by changes in cardiac output.
Databáze: OpenAIRE