Factors Associated with Acceptability, Consideration and Intention of Uptake of Direct-To-Consumer Genetic Testing
| Autor: | Maurice P. Zeegers, Liesbeth van Osch, Anke Wesselius, Annemie M. W. J. Schols, Hein de Vries, Dasa Kokole, Kelly F. J. Stewart |
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| Přispěvatelé: | Complexe Genetica, RS: NUTRIM - R3 - Respiratory & Age-related Health, Promovendi NTM, RS: CAPHRI - R6 - Promoting Health & Personalised Care, Health promotion, Promovendi PHPC, Pulmonologie, RS: CAPHRI - R5 - Optimising Patient Care |
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Male
0301 basic medicine Health Knowledge Attitudes Practice Cross-sectional study Applied psychology Distribution (economics) Intention 030105 genetics & heredity Innovativeness Direct-to-consumer genetic testing Acceptability Survey study Surveys and Questionnaires Health care Consideration Precision Medicine Genetics (clinical) Netherlands education.field_of_study medicine.diagnostic_test Linear model Survey research Middle Aged Knowledge Order (business) PUBLIC KNOWLEDGE General public Female HEALTH Psychology Research Article Adult AWARENESS Adolescent Decision Making Population Young Adult 03 medical and health sciences Direct-To-Consumer Screening and Testing medicine Humans Genetic Testing ATTITUDES education Aged Genetic testing business.industry Public Health Environmental and Occupational Health Cross-Sectional Studies Attitude Public Opinion business GENOMICS |
| Zdroj: | Public Health Genomics, 21(1-2), 45-52. Karger |
| ISSN: | 1662-4246 |
| Popis: | Background: With interest in personalised health care growing, so is interest in personal genetic testing. This is now offered direct-to-consumer, thereby referred to as direct-to-consumer genetic testing (DTC-GT). Criticisms have been expressed on whether a truly informed decision to undergo testing is made with regard to these services. In order to provide relevant information to achieve this, knowing the characteristics of the expected user population is helpful. Therefore, the aim of this study is to identify characteristics of individuals who (1) find the concept of DTC-GT acceptable and (2) consider undergoing DTC-GT in the distant or near future. Methods: This cross-sectional study investigated factors associated with acceptability, consideration and intention in the Dutch general population. Studied variables included awareness, principles and how-to knowledge, attitude, innovativeness, and multiple demographic characteristics. Generalised linear models were applied to identify associated variables. Results: Full data was obtained for 836 respondents. Of those, 18.3% found DTC-GT somewhat or totally acceptable, whereas 12.6% considered and 5.5% intended to undergo DTC-GT in the distant or near future. Acceptability was greater with lower principles knowledge, and consideration and intention with lower how-to knowledge. A more positive attitude and greater innovativeness were associated with an increase in all 3 outcomes. Conclusion: Informed decision making may be hampered as individuals with lower how-to knowledge were found to be more interested in pursuing testing. The identified characteristics can be used in development and distribution of public and personalized information, in order to help consumers make a truly informed decision. |
| Databáze: | OpenAIRE |
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