Diagnostic Accuracy of Screening Arterial Spin-Labeling MRI Using Hadamard Encoding for the Detection of Reduced CBF in Adult Patients with Ischemic Moyamoya Disease
| Autor: | Tsuyoshi Matsuda, Takayuki Chiba, Masakazu Kobayashi, Kuniaki Ogasawara, Kunihiro Yoshioka, Makoto Sasaki, Yoshitaka Kubo, Michiyasu Suzuki, Shunrou Fujiwara, Kengo Setta, Kenji Yoshida |
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| Rok vydání: | 2021 |
| Předmět: |
Adult
Perfusion scanning 030218 nuclear medicine & medical imaging 03 medical and health sciences Imaging Three-Dimensional 0302 clinical medicine Text mining Cerebellar hemisphere medicine Humans Radiology Nuclear Medicine and imaging Moyamoya disease Revascularization surgery Receiver operating characteristic Adult patients business.industry Adult Brain medicine.disease Magnetic Resonance Imaging Cerebrovascular Circulation Cerebral hemisphere Spin Labels Neurology (clinical) Moyamoya Disease Nuclear medicine business 030217 neurology & neurosurgery |
| Zdroj: | AJNR Am J Neuroradiol |
| ISSN: | 1936-959X 0195-6108 |
| Popis: | BACKGROUND AND PURPOSE: Adult patients with ischemic Moyamoya disease are advised to undergo selective revascularization surgery based on cerebral hemodynamics. The purpose of this study was to determine the diagnostic accuracy of arterial spin-labeling MR imaging using Hadamard-encoded multiple postlabeling delays for the detection of reduced CBF in such patients. MATERIALS AND METHODS: Thirty-seven patients underwent brain perfusion SPECT and pseudocontinuous arterial spin-labeling MR imaging using standard postlabeling delay (1525 ms) and Hadamard-encoded multiple postlabeling delays. For Hadamard-encoded multiple postlabeling delays, based on data obtained from the 7 sub-boluses with combinations of different labeling durations and postlabeling delays, CBF corrected by the arterial transit time was calculated on a voxel-by-voxel basis. Using a 3D stereotaxic template, we automatically placed ROIs in the ipsilateral cerebellar hemisphere and 5 MCA territories in the symptomatic cerebral hemisphere; then, the ratio of the MCA to cerebellar ROI was calculated. RESULTS: The area under the receiver operating characteristic curve for detecting reduced SPECT-CBF ratios ( |
| Databáze: | OpenAIRE |
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