Noninvasive stress testing of myocardial ischemia: comparison of GRE-MRI perfusion and wall motion analysis to 99 mTc-MIBI-SPECT, relation to coronary angiography
| Autor: | J. Müller-Brand, Christoph Gradel, Matthias Pfisterer, Georg Bongartz, Jens Bremerich, P. Buser, Wolfgang Steinbrich |
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| Rok vydání: | 1997 |
| Předmět: |
Male
Technetium Tc 99m Sestamibi medicine.medical_specialty Vasodilator Agents Stress testing Ischemia Myocardial Ischemia Contrast Media Magnetic Resonance Imaging Cine Perfusion scanning Gadolinium Coronary Angiography Sensitivity and Specificity Coronary artery disease Electrocardiography Heterocyclic Compounds Coronary Circulation medicine Organometallic Compounds Humans Radiology Nuclear Medicine and imaging Neuroradiology Tomography Emission-Computed Single-Photon medicine.diagnostic_test business.industry Magnetic resonance imaging General Medicine Dipyridamole Middle Aged medicine.disease Myocardial Contraction Feasibility Studies Radiology business Nuclear medicine Perfusion medicine.drug |
| Zdroj: | European radiology. 7(7) |
| ISSN: | 0938-7994 |
| Popis: | In the evaluation of ischemic heart disease only MR imaging seems to have the potential to assess myocardial perfusion, function, and coronary morphology on a single instrument. The aim of this study was to assess the feasibility of a stress test with dipyridamole (0. 56 mg/kg) to analyze myocardial perfusion by Gd first-pass enhancement in ultrafast gradient-recalled-echo MRI (perf-MRI), and wall motion by cine gradient-recalled-echo MRI (Cine-MRI) in one imaging session. Twelve patients underwent complete rest and stress studies; satisfactory MR images were acquired in 10 patients. By 99 mTc-MIBI-SPECT sensitivities to detect ischemic segments were 66.7 % with Perf-MRI, 80.0 % with WM-MRI and 86.7 % for Perf-WM-MRI (Perf-MRI vs Perf-WM-MRI; p = 0.03). Scar was equally detected with a sensitivity of 91.6 % with either MRI technique. Thus, Perf-Cine-MRI provides complementary information for the management of ischemic heart disease and has a higher sensitivity than Perf-MRI alone. |
| Databáze: | OpenAIRE |
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