Neuropsychological function in patients with end-stage heart failure before and after cardiac transplantation
| Autor: | Robert A. Bornstein, R. C. Starling, P. D. Myerowitz, G. J. Haas |
|---|---|
| Rok vydání: | 1995 |
| Předmět: |
Adult
Cardiomyopathy Dilated Male medicine.medical_specialty Heart disease medicine.medical_treatment Intelligence Cardiac index Cardiomyopathy Myocardial Ischemia Neuropsychological Tests Postoperative Complications Internal medicine medicine Humans Heart transplantation Cerebral Cortex Heart Failure business.industry Neuropsychology Hemodynamics General Medicine Stroke volume Middle Aged medicine.disease Surgery Transplantation Neurology Heart failure Cardiology Heart Transplantation Brain Damage Chronic Female Neurology (clinical) business Cognition Disorders Follow-Up Studies |
| Zdroj: | Acta neurologica Scandinavica. 91(4) |
| ISSN: | 0001-6314 |
| Popis: | This study was performed to examine cognitive function in patients with end-stage heart failure, to identify possible cardiovascular factors associated with cognitive function, and to evaluate changes in cognitive function in a subgroup of patients who received heart transplantation. An extensive battery of neuropsychological tests were given to 62 patients with end-stage cardiac failure as part of their evaluation for cardiac transplantation. Most patients were consecutive referrals, not selected because of cognitive complaints. A small subgroup of transplanted (n = 7) and non-transplanted (n = 4) patients received a repeat neuropsychological examination. At initial examination, approximately 50% of the patients met criteria for impairment in reference to normal control values. Higher stroke volume index and cardiac index and lower right atrial pressure were correlated with better cognitive function. In the subgroup of patients re-examined, the transplanted patients demonstrated significantly improved cognitive function, whereas the non-transplanted subjects were unchanged. These data indicate that in patients with end-stage heart failure there is a high prevalence of impaired cognitive function which is related to measures of cardiovascular efficiency. Preliminary evidence suggests that these impairments may be partially ameliorated by cardiac transplantation. |
| Databáze: | OpenAIRE |
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