Functional circulation and blood-brain permeability images by Angio CT in the assessment of cerebral ischemia
| Autor: | M. Furlan, A. Bartolini, G. Trivelli, B. Gasparetto, L. Sullo, R. Amore, A. Primavera |
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| Rok vydání: | 1994 |
| Předmět: |
Time Factors
Ischemia Hemodynamics Contrast Media Health Informatics Blood–brain barrier Permeability Brain Ischemia medicine Humans Radiology Nuclear Medicine and imaging Vertebral Artery Blood Volume Radiological and Ultrasound Technology medicine.diagnostic_test business.industry Vascular disease Brain Blood flow Cerebral Infarction medicine.disease Computer Graphics and Computer-Aided Design Cerebral Angiography Radiographic Image Enhancement Contrast medium Cerebrovascular Disorders medicine.anatomical_structure Carotid Arteries Blood-Brain Barrier Basilar Artery Cerebrovascular Circulation Angiography Data Display Computer Vision and Pattern Recognition Tomography business Nuclear medicine Tomography X-Ray Computed |
| Zdroj: | Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society. 18(3) |
| ISSN: | 0895-6111 |
| Popis: | We performed rapid sequential computerized tomography (CT) scanning following i.v. injection of a bolus of contrast medium, and generated three functional images related, respectively, to intravascular circulation time (rABCT), vascular volume density (Vv) and blood-brain barrier (BBB) unidirectional constant uptake rate (Ki). This was accomplished by calculating the first mathematical moment of the monitored time-density curves about the injection time, and by the multiple time graph analysis described by Patlack and coworkers. A satisfactory resolution was achieved, allowing separate appreciation of changes in rABCT both at large vessels and at tissue small vessels. Combined evaluation of rABCT and Vv images allowed us to draw qualitative conclusions about blood flow and perfusion reserve. |
| Databáze: | OpenAIRE |
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