A Reverse Flow-Metabolism Mismatch Pattern
| Autor: | Kaname Akioka, Kazuhide Takeuchi, Yuji Sakanoue, Iku Toda, Hironobu Ochi, Hiroyuki Yamagishi, Junichi Yoshikawa, Minoru Yoshiyama, Masakazu Teragaki, Kumiko Hirata |
|---|---|
| Rok vydání: | 2000 |
| Předmět: |
Male
medicine.medical_specialty Physiology Myocardial Infarction Ischemia Hemodynamics Cohort Studies Contractility Electrocardiography Coronary circulation Ammonia Fluorodeoxyglucose F18 Coronary Circulation Dobutamine Internal medicine medicine Humans Aged Fluorodeoxyglucose Nitrogen Isotopes Chemistry Myocardium Blood flow Middle Aged medicine.disease Myocardial Contraction medicine.anatomical_structure Echocardiography Regional Blood Flow Cardiovascular agent Cardiology Female Radiopharmaceuticals Cardiology and Cardiovascular Medicine Biomarkers Tomography Emission-Computed medicine.drug |
| Zdroj: | Japanese Circulation Journal. 64:659-666 |
| ISSN: | 1347-4839 0047-1828 |
| Popis: | Few studies have investigated the contractility of myocardium with a reverse flow-metabolism pattern; that is, greater uptake of nitrogen- 13-ammonia (NH3) than fluorine- 18-fluorodeoxyglucose (FDG) on positron emission tomography (PET). This study examined the contraction thickening represented by count increase in ECG-gated FDG-PET of myocardium with a reverse flow-metabolism pattern during low-dose dobutamine stress. Fifty-four patients with myocardial infarction were studied. Relative NH3 and FDG uptake (%NH3, %FDG) and %count increase were measured in 216 apical and 216 lateral segments on ECG-gated FDG-PET. The %count increase during low-dose dobutamine stress was greater in myocardium with a reverse flow-metabolism mismatch pattern than in myocardium with a flow-metabolism mismatch pattern (35.9+/-25.7% vs 24.6+/-15.9%, p=0.0221 in apical segments, and 38.4+/-22.6% vs 27.6+/-18.4%, p=0.0040 in lateral segments) despite smaller %FDG. A reverse flow-metabolism mismatch pattern should be noted as a new marker of viable myocardium with greater contractility during dobutamine stress than myocardium with a flow-metabolism mismatch pattern. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|