THE ROLE OF ADIPOSE TISSUE AND LABORATORY PREDICTORS OF PRIMARY OSTEOPOROSIS
| Autor: | V. L. Emanuel, N. L. Denisov, L. A. Kornoukhova |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Male
medicine.medical_specialty Osteoporosis Adipose tissue 030209 endocrinology & metabolism 03 medical and health sciences 0302 clinical medicine Internal medicine medicine Humans Metabolic Syndrome Postmenopausal women business.industry Biochemistry (medical) General Medicine Alkaline Phosphatase medicine.disease Medical Laboratory Technology Endocrinology Adipose Tissue Liver Alkaline phosphatase Calcium Female 030211 gastroenterology & hepatology Primary osteoporosis Total calcium Metabolic syndrome business Liver pathology |
| Zdroj: | Russian Clinical Laboratory Diagnostics. 65:205-211 |
| ISSN: | 0869-2084 |
| DOI: | 10.18821/0869-2084-2020-65-4-205-211 |
| Popis: | The purpose of this work was to determine the information content of alkaline phosphatase (ALP), total calcium (Ca) as predictors for the diagnosis of osteoporosis. By laboratory methods, 2451 people were divided into two groups according to the presence/absence of metabolic syndrome (MetS+ / MetS-): 1946 women (MetS- 1119, MetS+ 827) and 505 men (MetS- 264, MetS+ 241). Patients with laboratory signs of liver pathology are excluded. In women: MetS+ levels of ALP and Ca significantly differ from MetS- (p< 0.0001), no differences were found for men. ALP synchronously change the indicators of TG, HDL, LDL, ALT, AST, Ca, demonstrating a positive relationship (p< 0.001), the indicators do not exceed the threshold values. MetS- women in pre- and postmenopausal women significantly differ in ALP: 63.90 E / l vs 79.10 E / l (p |
| Databáze: | OpenAIRE |
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