Molecular epidemiology of Echinococcus species in Pakistan
Autor: | Aisha Khan, Haroon Ahmed, Sami Simsek |
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Rok vydání: | 2018 |
Předmět: |
0301 basic medicine
lcsh:Arctic medicine. Tropical medicine lcsh:RC955-962 030231 tropical medicine Population Zoology Echinococcus multilocularis 03 medical and health sciences 0302 clinical medicine parasitic diseases medicine education Echinococcus granulosus education.field_of_study biology Molecular epidemiology business.industry General Medicine 030108 mycology & parasitology medicine.disease biology.organism_classification Echinococcosis Echinococcus Parasitic disease Molecular Genotyping Pakistan Livestock business geographic locations |
Zdroj: | Asian Pacific Journal of Tropical Medicine, Vol 11, Iss 13, Pp 36-36 (2018) |
ISSN: | 1995-7645 |
Popis: | Objective: Cystic echinococcosis (CE) is a zoonotic parasitic disease and a neglected infectious disease affecting more than one million people globally. It is caused by the tapeworm parasite of Echinococcus granulosus sensu lato. It is endemic in the neighbours of Pakistan. However, there are limited studies on molecular epidemiology of CE in Pakistan. Methods: Discrimination of Echinococcus species has been done mostly by morphologically and less work has been done by molecular methods in Pakistan. There are limited studies have been conducted to explore the molecular epidemiology of Echinococcus species in human and livestock. In human just retrospective studies have been conducted and there is a serious lack of studies on molecular basis. Results: So far in Pakistan just four studies have been published on genotyping of Echinococcus spp. common sheep strain (G1) and buffalo strain (G3) in livestock (small and large ruminants) and Echinococcus granulosus sensu stricto (G1-G3) in buffaloes, while Echinococcus granulosus sensu stricto (G1-G3), Echinococcus multilocularis, Echinococcus canadensis (G6/7) in human have been reported. Based on these four studies clearly shows that CE is yet neglected in Pakistan. These findings indicate that due to the higher population of sheep and buffaloes, G1 and G3 strains are highly prevalent in human and animals. Association of stray dogs with sheep herds and other livestock at the grazing sites is responsible for the higher prevalence of CE that acts an active role in the transmission of CE while the wild animals and camel are responsible for the less infection. Conclusion: There is dire need of more studies on molecular identification of CE to understand its species diversity and molecular epidemiology in Pakistan. It is an important step toward management of echinococcosis based on One Health Concept. |
Databáze: | OpenAIRE |
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