Real-World Performance of the MiniMed™ 780G System: First Report of Outcomes from 4120 Users
| Autor: | Benyamin Grosman, Javier Castañeda, Giuseppe Lepore, Ohad Cohen, Julien Da Silva, Tadej Battelino, John H. Shin, Arcelia Arrieta |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Blood Glucose
medicine.medical_specialty Endocrinology Diabetes and Metabolism MEDLINE Time-in-range Endocrinology Insulin Infusion Systems Diabetes mellitus Internal medicine medicine Humans Hypoglycemic Agents Insulin Retrospective Studies Real-world evidence business.industry Blood Glucose Self-Monitoring Diabetes Basal bolus Original Articles medicine.disease Hypoglycemia Medical Laboratory Technology Diabetes Mellitus Type 1 Basal (medicine) Hyperglycemia Automated insulin delivery Cardiology business Closed loop |
| Zdroj: | Diabetes Technology & Therapeutics |
| ISSN: | 1557-8593 |
| Popis: | Background: The MiniMed™ 780G system includes an advanced hybrid closed loop (AHCL) algorithm that provides both automated basal and correction bolus insulin delivery. The preliminary performance of the system in real-world settings was evaluated. Methods: Data uploaded from August 2020 to March 2021 by individuals living in Belgium, Finland, Italy, the Netherlands, Qatar, South Africa, Sweden, Switzerland, and the United Kingdom were aggregated and retrospectively analyzed to determine the mean glucose management indicator (GMI), percentage of time spent within (TIR), below (TBR), and above (TAR) glycemic ranges, system use, and insulin consumption in users having ≥10 days of sensor glucose (SG) data after initiating AHCL. The impact of initiating AHCL was evaluated in a subgroup of users also having ≥10 days of SG data, before AHCL initiation. Results: Users (N = 4120) were observed for a mean of 54 ± 32 days. During this time, they spent a mean of 94.1% ± 11.4% of the time in AHCL and achieved a mean GMI of 6.8% ± 0.3%, TIR of 76.2% ± 9.1%, TBR 180 of 21.3% ± 9.4%, after initiating AHCL. There were 77.3% and 79.0% of users who achieved a TIR >70% and a GMI of 70% (34.6% vs. 74.9%, P 70% and GMI |
| Databáze: | OpenAIRE |
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