Symmetrical and Asymmetrical Cyanine Dyes. Synthesis, Spectral Properties, and BSA Association Study
| Autor: | Antônio César de Amorim Borges, Leandra Franciscato Campo, Fabiano Severo Rodembusch, Cesar Liberato Petzhold, Letícia Todeschini, Diego dos Santos Pisoni |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
chemistry.chemical_classification
biology Nitrogen Ultraviolet Rays Organic Chemistry Spectral properties Serum albumin Serum Albumin Bovine Buffers Carbocyanines Photochemistry Fluorescence Solutions Chain length chemistry.chemical_compound chemistry Yield (chemistry) biology.protein Organic chemistry Cyanine Bovine serum albumin Coloring Agents Alkyl Fluorescent Dyes |
| Zdroj: | The Journal of Organic Chemistry. 79:5511-5520 |
| ISSN: | 1520-6904 0022-3263 |
| DOI: | 10.1021/jo500657s |
| Popis: | New cyanines were prepared by an efficient and practical route with satisfactory overall yield from low-cost starting materials. The photophysical behavior of the cyanines was investigated using UV-vis and steady-state fluorescence in solution, as well as their association with bovine serum albumin (BSA) in phosphate buffer solution (PBS). No cyanine aggregation was observed in organic solvents or in phosphate buffer solution. The alkyl chain length in the quaternized nitrogen was shown to be fundamental for BSA detection in PBS in these dyes. |
| Databáze: | OpenAIRE |
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