The S-oxidation of S-carboxymethyl-L-cysteine in hepatic cytosolic fractions from BTBR and phenylketonuria enu1 and enu2 mice

Autor:	Glyn B. Steventon, Stephen C. Mitchell
Rok vydání:	2018
Předmět:	S-carboxymethyl-L-cysteine Male Phenylalanine hydroxylase Health Toxicology and Mutagenesis Phenylalanine Toxicology medicine.disease_cause 030226 pharmacology & pharmacy Biochemistry Substrate Specificity 03 medical and health sciences Mice 0302 clinical medicine Cytosol Phenylketonurias polycyclic compounds medicine Animals Enzyme kinetics Pharmacology Mutation biology Chemistry Carbocysteine Phenylalanine Hydroxylase General Medicine Monooxygenase Molecular biology Mice Mutant Strains Kinetics Liver 030220 oncology & carcinogenesis biology.protein Female S oxidation Oxidation-Reduction
Zdroj:	Xenobiotica; the fate of foreign compounds in biological systems. 49(4)
ISSN:	1366-5928
Popis:	Mice that were heterozygous dominant for the enu1 and enu2 mutation in phenylalanine monooxygenase/phenylalanine hydroxylase (PAH) resulted in hepatic PAH assays for S-carboxymethyl-L-cysteine (SCMC) that had significantly increased calculated K
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6240ebfe6c2998dc77f3b1c1edbf42c https://pubmed.ncbi.nlm.nih.gov/29648495 Zobrazit plný text záznamu