Significance of the Diagnosis of Executive Functions in Patients with Relapsing-Remitting Multiple Sclerosis
| Autor: | Beata Daniluk, Katarzyna Adamczyk, Aneta R. Borkowska |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Adult
cognition medicine.medical_specialty Health Toxicology and Mutagenesis Audiology Neuropsychological Tests multiple sclerosis Article Executive Function Young Adult Multiple Sclerosis Relapsing-Remitting medicine Verbal fluency test Humans Neuropsychological assessment Cognitive skill Cognitive decline Cognitive deficit medicine.diagnostic_test business.industry Public Health Environmental and Occupational Health Middle Aged Executive functions executive functions neuropsychological assessment depression Medicine medicine.symptom business Cognition Disorders Porteus Maze Test Stroop effect |
| Zdroj: | International Journal of Environmental Research and Public Health Volume 18 Issue 19 International Journal of Environmental Research and Public Health, Vol 18, Iss 10527, p 10527 (2021) |
| ISSN: | 1660-4601 |
| DOI: | 10.3390/ijerph181910527 |
| Popis: | Multiple sclerosis (MS) is a progressive chronic disease of the Central Nervous System (CNS). Cognitive decline occurs rather rarely in relapsing–remitting multiple sclerosis (RRMS) compared to other types. The present study aimed to assess executive functions (EF) in relation to clinical and demographic variables in patients with RRMS. The study involved 22 individuals with RRMS (aged 23 to 49 years) and 22 matching controls. All the individuals with RRMS were in the remission phase. The assessments were carried out using MoCA, BDI-II, Halstead Category Test, Porteus Maze Test, verbal fluency tasks and Stroop Colour-Word Interference Test. The findings show that the two groups differed significantly in all the tests. All patients with RRMS in the remission phase presented at least one cognitive deficit, observed in general cognitive functioning, abstract reasoning or other executive functions, i.e., fluency, interference suppression, planning, or ability to modify activity in response to feedback. The deficits in most cases (except for those measured with the MoCA, Category Tests and phonemic fluency), are not related to intensity of depression and duration of the disease. Findings suggest that the diagnostic process in the case of patients with RRMS may include psychological assessment focusing on potentially existing cognitive, mainly executive, deficits and their severity. |
| Databáze: | OpenAIRE |
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