Skin Protection by Sucralfate Cream During Electron Beam Therapy
| Autor: | P. Gröhn, O.-P. Isokangas, A. G. Maiche |
|---|---|
| Rok vydání: | 1994 |
| Předmět: |
Adult
medicine.medical_specialty Erythema Sucralfate medicine.medical_treatment Breast Neoplasms Radiation-Protective Agents Radiotherapy High-Energy Breast cancer Double-Blind Method medicine Humans Radiology Nuclear Medicine and imaging Postoperative Period Radiation Injuries skin and connective tissue diseases Aged Skin Aged 80 and over Skin protection integumentary system business.industry digestive oral and skin physiology food and beverages Hematology General Medicine Middle Aged medicine.disease Dermatology Radiation therapy Moist desquamation Oncology Electron Beam Therapy Female Radiation reaction medicine.symptom business medicine.drug |
| Zdroj: | Acta Oncologica. 33:201-203 |
| ISSN: | 1651-226X 0284-186X |
| Popis: | Acute skin reactions, such as erythema and moist desquamation, constitute major problems during radiotherapy of superficially located tumours. There are no drugs available for the skin care. Sucralfate, a widely used anti-ulcer drug, has anti-inflammatory properties, and it activates cell proliferation. Based on these data and our previous experience of sucralfate cream on the aging skin we performed a double-blind randomized study to compare the efficacy of sucralfate cream to a base cream in 50 breast cancer patients receiving postoperative electron beam therapy to their chest wall. The acute radiation reaction of the skin was statistically significantly prevented by the sucralfate cream. The recovery of the skin was also significantly faster in the sucralfate cream group. Side-effects due to the cream were rare. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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