Genetic predisposition plays a role in nigral cell death in Parkinson's disease

Autor:	J.H. Kurth, M.C. Kurth
Rok vydání:	1999
Předmět:	Genetics Parkinson's disease Disease Biology medicine.disease Human genetics Neurology Etiology Genetic predisposition medicine Identification (biology) Neurology (clinical) Geriatrics and Gerontology Gene Genetic association
Zdroj:	Parkinsonism & Related Disorders. 5:169-172
ISSN:	1353-8020
Popis:	Both genetic and environmental factors are involved in the etiology of Parkinson's disease (PD). The recent identification of specific autosomal genes that lead to variants of PD confirms that genetic factors are important. Identifying and confirming other genetic factors responsible for PD is a difficult task because PD is a complex disease, the results of multiple genetic and environmental factors leading to a final common pathology. This review will discuss how advances in human genetics will allow future unraveling of the complex interactions between genetics and environment in the etiology of PD.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a613daf004744f192ce0a5c99b5731a3 https://doi.org/10.1016/s1353-8020(99)00033-4 Zobrazit plný text záznamu Full Text from ScienceDirect